Autologous Fat Grafting on the Right Leg : Sebuah Laporan Kasus

Authors

  • Fory Fortuna Universitas Andalas
  • Raina Rasikarahma Universitas Andalas

DOI:

https://doi.org/10.56260/sciena.v1i5.74

Keywords:

Autologous, fat, graft, liposuction, cruris, dextra

Abstract

Pendahuluan: Autologous fat grafting menjadi semakin populer beberapa tahun terakhir dengan banyaknya aplikasi rekonstruksi pada payudara, wajah, pasca radiasi dan luka bakar, anomali kongenital, serta berbagai aplikasi estetika. Keuntungan prosedur ini adalah menggunakan bahan dari tubuh sendiri sehingga kecil kemungkinan terjadi reaksi alergi, jumlah lemak donor yang cukup banyak tersedia, serta dapat bertahan dalam beberapa tahun. Prosedur ini merupakan prosedur berisiko rendah dengan potensi komplikaisi seperti nekrosis lemak, pembentukan kista, selulitis, serta ketidakteraturan kontur. Metode: Pada laporan kasus ini akan dicantumkan tinjauan kepustakaan mengenai autologous fat grafting, serta laporan kasus dan diskusi. Pasien perempuan berusia 25  tahun datang ke poliklinik Bedah Plastik Rumah Sakit M.Djamil Padang dengan keluhan bekas luka pada betis kanan dan kulit terlihat mencekung pada bekas luka. Hasil: Pasien kemudian dilakukan liposuction dan fat graft pada cruris dextra dan diberikan obat pulang berupa antiyeri. Pada pasien ini terapi post operatif luka ditutup dengan menggunakan kasa dan plester kemudian disarankan untuk kontrol setiap bulannya.

Author Biographies

Fory Fortuna, Universitas Andalas

Fakultas Kedokteran

Raina Rasikarahma, Universitas Andalas

Fakultas Kedokteran

References

. Thorne CH. Grabb and Smith’s Plastic Surgery. 8th Editio. Philadelphia: Lippincott Williams & Willkins; 2014.

. Shauly O, Gould DJ, Ghavami A. Fat Grafting: Basic Science, Techniques, and Patient Management. Plast Reconstr Surg - Glob Open. 2022;10(3):E3987: 1-2

. Perdanakusuma A, Primawati A, Dr B. Microautologous Fat Transplantation (MAFT) sebagai Rekonstruksi Lanjutan pada Kasus Deformitas Maksilofasial Pasca Trauma. J Rekonstruksi dan Estet. 2021;6(2):43.

. Xue EY, Narvaez L, Chu CK, Hanson SE. Fat Processing Techniques. Semin Plast Surg. 2020;34(1):11–6.

. Shauly O, Gould DJ, Ghavami A. Fat Grafting: Basic Science, Techniques, and Patient Management. Plast Reconstr Surg - Glob Open. 2022;10(3):E3987: 3-7

. Camison L, Naran S, Lee WW, et al. Hyperbaric oxygen therapy for large composite grafts: an alternative in pediatric facial reconstruction. J Plast Reconstr Aesthet Surg. 2020;73:2178–2184.

. Gardin C, Bosco G, Ferroni L, et al. Hyperbaric oxygen therapy improves the osteogenic and vasculogenic properties of mesenchymal stem cells in the presence of inflammation in vitro. Int J Mol Sci. 2020;21:E1452.

. Fisher C, Grahovac TL, Schafer ME, et al. Comparison of harvest and processing techniques for fat grafting and adipose stem cell isolation. Plast Reconstr Surg. 2013;132:351–361.

. Strong AL, Cederna PS, Rubin JP, et al. The current state of fat grafting: a review of harvesting, processing, and injection techniques. Plast Reconstr Surg. 2015;136:897–912.’

. Fontes T, Brandão I, Negrão R, et al. Autologous fat grafting: harvesting techniques. Ann Med Surg (Lond). 2018;36:212–218.

. Gir P, Brown SA, Oni G, et al. Fat grafting: evidence-based review on autologous fat harvesting, processing, reinjection, and storage. Plast Reconstr Surg. 2012;130:249–258.

. Pu LLQ, Coleman SR, Cui X, et al. Autologous fat grafts harvested and refined by the Coleman technique: a comparative study. Plast Reconstr Surg. 2008;122:932–937.

. Smith P, Adams WP Jr, Lipschitz AH, et al. Autologous human fat grafting: effect of harvesting and preparation techniques on adipocyte graft survival. Plast Reconstr Surg. 2006;117:1836–1844.

. Sommer B, Sattler G. Current concepts of fat graft survival: histology of aspirated adipose tissue and review of the literature. Dermatol Surg. 2000;26:1159–1166.

. Agostini T, Lazzeri D, Pini A, et al. Wet and dry techniques for structural fat graft harvesting: histomorphometric and cell viability assessments of lipoaspirated samples. Plast Reconstr Surg. 2012;130:331e–339e.

. Geissler PJ, Davis K, Roostaeian J, et al. Improving fat transfer viability: the role of aging, body mass index, and harvest site. Plast Reconstr Surg. 2014;134:227–232.

. Shiffman MA, Mirrafati S. Fat transfer techniques: the effect of harvest and transfer methods on adipocyte viability and review of the literature. Dermatol Surg. 2001;27:819–826.

. Fournier P. Microlipoextraction et microlipoinjection. Rev Chir Esthet Lang Franc. 1985;10.

. Fournier PF. Liposculpture: the syringe technique. Am J Cosmet Surg. 1993;10:179–187.

. Klein JA. Tumescent technique for regional anesthesia permits lidocaine doses of 35mg/kg for liposuction. J Dermatol Surg Oncol. 1990;16:248–263.

. Girard AC, Atlan M, Bencharif K, et al. New insights into lidocaine and adrenaline effects on human adipose stem cells. Aesthetic Plast Surg. 2013;37:144–152.

. Keck M, Janke J, Ueberreiter K. Viability of preadipocytes in vitro: the influence of local anesthetics and pH. Dermatol Surg. 2009;35:1251–1257

. Moore JH Jr, Kolaczynski JW, Morales LM, et al. Viability of fat obtained by syringe suction lipectomy: effects of local anesthesia with lidocaine. Aesthetic Plast Surg. 1995;19:335–339.

. Keck M, Zeyda M, Gollinger K, et al. Local anesthetics have a major impact on viability of preadipocytes and their differentiation into adipocytes. Plast Reconstr Surg. 2010;126:1500–1505.

. Coleman SR. Structural fat grafting. Aesthet Surg J. 1998;18:386–388.

. Egro FM, Coleman SR. Facial fat grafting: the past, present, and future. Clin Plast Surg. 2020;47:1–6.

. Coleman SR. Structural fat grafting. Plast Reconstr Surg. 2005;115:1777–1778.

. Campbell GL, Laudenslager N, Newman J. The effect of mechanical stress on adipocyte morphology and metabolism. Am J Cosmet Surg. 1987;4:89–94.

. Ross RJ, Shayan R, Mutimer KL, et al. Autologous fat grafting: current state of the art and critical review. Ann Plast Surg. 2014;73:352–357.

. Zhu M, Cohen SR, Hicok KC, et al. Comparison of three different fat graft preparation methods: gravity separation, centrifugation, and simultaneous washing with filtration in a closed system. Plast Reconstr Surg. 2013;131:873–880.

. Canizares O Jr, Thomson JE, Allen RJ Jr, et al. The effect of processing technique on fat graft survival. Plast Reconstr Surg. 2017;140:933–943.

. Crawford JL, Hubbard BA, Colbert SH, et al. Fine tuning lipoaspirate viability for fat grafting. Plast Reconstr Surg. 2010;126:1342–1348.

. Xue EY, Narvaez L, Chu CK, et al. Fat processing techniques. Semin Plast Surg. 2020;34:11–16.

. Condé-Green A, de Amorim NF, Pitanguy I. Influence of decantation, washing and centrifugation on adipocyte and mesenchymal stem cell content of aspirated adipose tissue: a comparative study. J Plast Reconstr Aesthet Surg. 2010;63:1375–1381.

. Mojallal A, Shipkov C, Braye F, et al. Influence of the recipient site on the outcomes of fat grafting in facial reconstructive surgery. Plast Reconstr Surg. 2009;124:471–483.

. Oranges CM, Striebel J, Tremp M, et al. The preparation of the recipient site in fat grafting: a comprehensive review of the preclinical evidence. Plast Reconstr Surg. 2019;143:1099–1107.

. Oranges CM, Striebel J, Tremp M, et al. The impact of recipient site external expansion in fat grafting surgical outcomes. Plast Reconstr Surg Glob Open. 2018;6:e1649.’

. Kim SE, Lee JH, Kim TG, et al. Fat graft survival after recipient site pretreatment with fractional carbon dioxide laser. Ann Plast Surg. 2017;79:552–557.

. Sezgin B, Ozmen S, Bulam H, et al. Improving fat graft survival through preconditioning of the recipient site with microneedling. J Plast Reconstr Aesthet Surg. 2014;67:712–720.

. James IB, Bourne DA, DiBernardo G, et al. The architecture of fat grafting II: impact of cannula diameter. Plast Reconstr Surg. 2018;142:1219–1225.

. Kirkham JC, Lee JH, Medina MA III, et al. The impact of liposuction cannula size on adipocyte viability. Ann Plast Surg. 2012;69:479–481.

. Khouri RK, Kuru M. Closed system and method for atraumatic, low pressure, continuous harvesting, processing, and grafting of lipoaspirate. US Patent 0167613A1. July 10, 2008.

. Pu LL. Mechanisms of fat graft survival. Ann Plast Surg. 2016;77(Suppl 1):S84–S86.

. Harris WM, Plastini M, Kappy N, et al. Endothelial differentiated adipose-derived stem cells improvement of survival and neovascularization in fat transplantation. Aesthet Surg J. 2019;39:220–232.

. Silverman KJ, Lund DP, Zetter BR, et al. Angiogenic activity of adipose tissue. Biochem Biophys Res Commun. 1988;153:347–352.

. Xiong BJ, Tan QW, Chen YJ, et al. The effects of platelet-rich plasma and adipose-derived stem cells on neovascularization and fat graft survival. Aesthetic Plast Surg. 2018;42:1–8.

. Gentile P, Orlandi A, Scioli MG, et al. Concise review: adipose[1]derived stromal vascular fraction cells and platelet-rich plasma: Basic and clinical implications for tissue engineering therapies in regenerative surgery. Stem Cells Transl Med. 2012;1:230–236.

. Bourin P, Bunnell BA, Casteilla L, et al. Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT). Cytotherapy. 2013;15:641–648.

. Cai W, Yu LD, Tang X, et al. The stromal vascular fraction improves maintenance of the fat graft volume: a systematic review. Ann Plast Surg. 2018;81:367–371.

Downloads

Published

2022-09-05

How to Cite

Fortuna, F., & Rasikarahma, R. . (2022). Autologous Fat Grafting on the Right Leg : Sebuah Laporan Kasus. Scientific Journal, 1(5), 412–424. https://doi.org/10.56260/sciena.v1i5.74